social practice> Types of section> Science and Technology Research Institute Remote Research Internship Camp: Biomedical Direction
                            Science and Technology Research Institute Remote Research Internship Camp: Biomedical Direction
                            Project Category: Science and Engineering Internship Research
                            Enrollment quota: 20 people
                            Suitable for groups: high school students, undergraduates
                                                        Activity time: annual enrollment
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project's venue:

                                Beijing

Project purpose:

                                This project aims to provide students with an understanding and mastery of background knowledge and cutting-edge dynamics in various research fields based on classical experimental methods and literature reading methods.

project cost:

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I. Project introduction

This internship program is designed for students who plan to apply for biology, bioinformatics, biomedical, and medical. Students will work with Tsinghua University/Beijing Life Research Institute instructors to use classical experimental methods to explain and read the literature, so that students can understand and master the background knowledge and frontier dynamics of various research fields. After the internship, the instructor will issue a recommendation letter based on the student's performance.

Second, the project content

This internship program is based on the discussion of classic subjects and articles in the field of mainstream biological research such as cell death, therapeutic antibodies, HBV receptors, and autophagy, allowing students to understand the basic research content involved in various fields, and the research methods used. And possible future research directions, including the following aspects:

Understand the research history of programmed cell death, research ideas and the application of biochemical test methods in biomedical research;

Understand the basic concepts of therapeutic antibodies and develop classical targets for therapeutic antibodies;

Understand the discovery process and research ideas of HBV receptors;

Understand the research process of cell autophagy, research ideas and the application of genetic experimental methods in biomedical research.

Third, the strength of teachers

The teacher is a postdoctoral researcher at the Beijing Institute of Life Sciences. He studied at Tsinghua University/Beijing Institute of Life Sciences and received his Ph.D. in biology. During the Ph.D., the research on siRNA/Ago 4 complex in Arabidopsis cytoplasm and nucleus transport mechanism, apoptosis and necrotic small molecule inhibitors and autophagy in model organisms, etc. Support for a number of national key research projects, such as the Development Plan Project (973 Program), the National Natural Science Foundation, and the National Science and Technology Major Project. In 2017, he was responsible for the study of hepatitis B virus (HBV) and hepatitis D virus (HDV) neutralizing antibodies at the Beijing Institute of Life Sciences. The paper was published in important academic journals such as Elife (JCR Division 1 of the Chinese Academy of Sciences) and obtained international patents.

Fourth, enrollment objects and requirements

Most outstanding undergraduates and some excellent high school students plan to apply for biology, bioinformatics, biomedical, medical and other related majors. In order to enable students to better complete research projects, the project team will take the form of written examination and interview. Students are screened.

V. Itinerary

The distance of the remote scientific research project is one month. The specific class time can be arranged according to the needs of the students and the appropriate time. It has great flexibility. The instructor can help students to complete a complete professional field research task more deeply, comprehensively and systematically, let the students participate in the whole process of scientific research project, experience the basic process of scientific research, feel the charm of scientific research, and let the students Learn about the background and frontier dynamics of the field. In addition to regular research project discussion courses, students can consult relevant questions at any time during the project cycle, get professional guidance from the instructors, and establish their possible future research directions and research plans.The specific course schedule is as follows:

class

content

Related papers

First lecture

1. Understanding the history of programmed cell death

2. Understand the application of classical biochemical purification methods in biological research

3.Learn how to better understand the article about cell death

Xuesong Liu-1996-Cell-Induction of Apoptotic Program in Cell-Free Extracts- Requirement for dATP and Cytochrome c

Second lecture

1. Understand the research and development history of therapeutic antibodies

2. Understand the development of classical clinical therapeutic antibodies

3.Learn how to better understand articles about therapeutic antibodies

Andrew-2012-Nature review-Antibody therapy of cancer

Lecture 3

1. To understandingHBVReceptor discovery story

2. Understanding receptors can be used as a targetHBVTherapeutic drugs

3.Learn how to better understandHBVInfected article

Huan Yan-Elife-2012-Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus

Fourth lecture

1. Understand the research history of autophagy

2. Understand the application of classical genetic methods in biological research

3.Learn how to better understand the article about autophagy

Tian Ye-2010-Cell-C. elegans Screen Identifies Autophagy Genes Specific to Multicellular Organisms

Fifth lecture

1. Understand the basic components of a biological laboratory

2. Learn how to prepare basic biological experiments

3.Understand the basic experimental operation of protein separation gel

 

Experimental link